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Homozygous familial hypercholesterolemia: 25 percent LDL-C reduction with Mipomersen

Graves’ disease: Propylthiouracil linked to liver failure

Safety and efficacy of Sirolimus as an immunosuppressant have not been established in liver transplant patients

Neuropsychiatric events with leukotriene inhibitors: Montelukast, Zafirlukast and Zileuton

Avastin for treatment of glioblastoma multiforme

Hyponatremia: FDA has approved Samsca

Gastrointestinal perforation, skin lesions or ocular disorders associated with Tarceva

Secondary exposure to Testosterone gel

Inflammatory breast cancer: Lapatinib could be used to treat patients with aggressive form

Metastatic HER2+ breast cancer: a combination of Capecitabine, Vinorelbine, and Trastuzumab is promising option

Bevacizumab effective at delaying alkylator-refractory anaplastic oligodendroglioma progression

Anti-angiogenesis inhibitors may improve outcomes of patients with sex cord-stromal tumors

Rheumatoid arthritis: Anakinra, a modest benefit with some risk

Allergic reactions to Clopidogrel can be treated with steroids and antihistamines

Anti–TNF-alpha agents may be associated with increased risk for herpes zoster

Clopidogrel plus Aspirin reduces myocardial infarction risk in patients with acute coronary syndrome

Proton pump inhibitors interfere with Clopidogrel

Cladribine in patients with relapsing-remitting multiple sclerosis: two-year data

Antiepileptics associated with decreased bone mineral density

Methylthioninium in high intravenous doses should be avoided for patients being treated with serotonergic antidepressants

Ceftriaxone and Calcium-containing products may be used concomitantly in patients greater than 28 days of age

FDA has approved Simponi for rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis

Genentech: voluntary withdrawal of Raptiva from the U.S. market

A case of progressive multifocal leukoencephalopathy in a Raptiva patient

Sorafenib targets acute myeloid leukemia driven by mutant FLT3 gene

Sorafenib: older renal cancer patients appear to benefit from treatment

Genetic study sheds new light on lung adenocarcinoma

BRAF mutations in colorectal cancer cause resistance to anti-EGFR therapy

Cancer: new biomarkers can predict response to treatments

Everolimus prolongs progression-free survival in patients with metastatic kidney cancer who have failed on other treatments

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