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Progressive multifocal leukoencephalopathy in CellCept treated patients
Provigil associated with serious rash and psychiatric symptoms
Ductal carcinoma in situ: patients overestimate breast cancer risks
HPV-positive head and neck cancer patients have a better response and survival than HPV-negative patients
Additional changes to Ortho Evra, a birth control patch
Six infection-related deaths reported after treatment with MabCampath in patients with B-cell chronic lymphocytic leukemia
Tysabri to treat moderate-to-severe Crohn's disease: FDA has approved
Alpha-Linolenic acid in treatment for dry eye syndrome
Oxcarbazepine does not appear to prevent migraine
Additional trials have shown increased mortality and/or tumor progression with Epogen / Procrit and Aranesp
COPD: is Spiriva associated with increased risk of stroke ?
Reversal of hypoglycemia in animal model of glycogen storage disease type Ia
Neuropsychiatric events associated with Tamiflu
Lupus: blocked signals to immune cells extend their life and contribute to progression of disease
Crohn's disease: combined immunosuppression therapy better than conventional treatment
Avastin: VEGF neutralization can damage brain vessels
Immunosuppressants: Mycophenolate mofetil linked to specific birth defect pattern
Potential biomarkers for psychosis and cerebrovascular disease in patients with systemic lupus erythematosus
Biochemical bases of 1918 flu pandemic
Genetic variation to predict initial response to Warfarin identified
Endeavor, a drug-eluting stent for treatment of narrowed coronary arteries
WHI follow up study: risks of long-term combination hormone therapy outweigh benefits for postmenopausal women
Oral Terbinafine can be associated with rare but serious and life-threatening toxicities
Tysabri may cause liver injury
Arcalyst is first treatment for cryopyrin-associated periodic syndromes
Gastroesophageal reflux disease: FDA has approved Nexium for use in children ages 1-11 years
Relapsing-remitting multiple sclerosis: Rituximab shows promise
Rheumatoid arthritis: cardiovascular benefits of anti-TNF therapy
Acute coronary syndrome: patients at risk of adverse events within 3 months after stopping Clopidogrel treatment
Anemic cancer patients: erythropoiesis-stimulating agents increase risk of death
Oral Buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease
Risk of suicidal thoughts and behavior with antiepileptic drugs
Two deaths after HPV vaccine Gardasil
Importance of pneumococcal vaccination in cochlear implant recipients
Cervarix, a HPV vaccine, is not therapeutic in women with preexisting infection
Replagal for the treatment of Fabry disease
Golimumab improves psoriatic arthritis symptoms
DIM, a compound in broccoli, could boost immune system
Blocking angiogenesis signaling from inside cell may lead to serious health problems
Hypersensitivity reactions to Pregabalin
Varenicline: possible effects on driving and psychiatric illness
Zolpidem: adverse neurological and psychiatric reactions
Tesamorelin reduces abdominal fat accumulation and improves lipids in HIV-infected patients
Possible role of prolactin in breast cancer
Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
Antidepressants: daily use of SSRIs associated with increased risk of fracture in older adults
Postmenopausal women: Calcium plus vitamin D supplements may help prevent weight gain
Waist-to-hip ratio may better predict cardiovascular risk than body mass index
Maternal obesity prior to pregnancy associated with birth defects
ADHD appears to be associated with depressed dopamine activity in the brain
Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
Irinotecan plus Bevacizumab in the treatment of glioblastoma multiforme
NSAIDs and coxibs: balancing of cardiovascular and gastrointestinal risk
Short-acting beta-agonists associated with myocardial ischaemia
FDA: new warning for Nonoxynol 9 OTC contraceptive products
Ace inhibitors and sartans: not for use in pregnancy
Computed tomography screening may increase lung cancer diagnosis, but not decrease risk of death
Decompensated heart failure: Levosimendan does not improve survival, compared to Dobutamine
Rosiglitazone and Pioglitazone: cardiovascular safety
FDA has approved Kuvan for treatment of phenylketonuria
FDA: second safety warning on Duragesic
Recombinant human erythropoietins: new prescribing advice
Finasteride unlikely to induce high-grade prostate tumor
Supracervical hysterectomy not superior to total hysterectomy
Routine thyroid screening not recommended for pregnant women
Glioblastoma multiforme: Bevacizumab shows encouraging results in phase II study
Reports of deaths and serious cardiopulmonary reactions following the administration of ultrasound micro-bubble contrast agents
FDA has approved Bystolic, a beta-blocker, to treat hypertension
Acute coronary syndromes: treating depression may reduce cardiac risk
Invasive breast cancer: biomarkers predict risk years before the tumor develops
The WHI Dietary Modification Trial: low fat diet may lower risk of ovarian cancer
Long-term pharmacotherapy for obesity and overweight: modest weight loss
Serotonin receptor agonists, a faster class of antidepressants
Zolpidem and bizarre sleep related effects
Citalopram, an antidepressant, has shown early promise in treating agitation and psychotic symptoms of dementia
Genes linked to suicidal thinking during antidepressant treatment
HIJ-CREATE trial: Candesartan reduces the incidence of MACE in patients with impaired renal function in addition to reduction of new onset of diabetes mellitus
Increased mortality among patients treated with Cefepime
Transient increase in cervical cancer risk in oral contraceptive users
Voltaren Gel for treatment of pain associated with osteoarthritis
Type 2 diabetes: FDA has added boxed warning for heart-related Risks to Avandia
FDA has approved Nexavar for patients with inoperable hepatocellular carcinoma
FDA: Crestor approved to slow the progression of atherosclerosis in patients with elevated cholesterol
Chronic myeloid leukaemia: Imatinib proves safe and effective over the long term
Hepatitis C: Peginterferon alfa-2a reduces the virus but serious liver problems may progress
Selective serotonin reuptake inhibitors can double risk of gastrointestinal bleeding
Rimonabant is associated with severe adverse psychiatric events
Pioglitazone and Rosiglitazone may reduce bone density
Renal impairment associated with Zoledronic acid
Erythropoiesis-stimulating agents: FDA has strengthened boxed warnings and has approved other safety labeling changes
STEP study: an investigational HIV vaccine is not effective
Drug-induced pancreatitis
TNF-alpha inhibitors are associated with several serious reactions
Novartis has proposed improving Galvus risk/benefit profile through use of approved 50 mg once-daily and twice-daily doses instead of approved 100 mg once-daily
The endocannabinoid system
FDA has requested marketing suspension of Trasylol, an antifibrinolytic drug
Chronic hepatitis B: Viread more effective than Hepsera
Pegasys provides hepatitis C patients a second chance to achieve a cure after not responding to Peg-Intron
Higher intake of fish and Vitamin-D levels linked to lower risk of age-related macular disease
Chemotherapy with Avastin increases risk of arterial thromboembolic events
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