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iv Bisphosphonates and osteonecrosis of the jaw: elevated risk for patients with underlying malignant condition

Rosiglitazone associated with parotid gland enlargement

Aripiprazole may cause neuroleptic malignant syndrome

Parkinson's disease: medical management of Levodopa-associated motor complications

EMEA recommends withdrawal of medicinal products containing Veralipride

Increased incidence of fractures in female patients who received long-term treatment with Avandia for type 2 diabetes mellitus

The benefit-risk ratio of Rosiglitazone therapy is not defined

Review of data indicates that Phenylephrine requires further study to demonstrate efficacy and safety

Potentially life threatening side effects combining Aliskiren with Valsartan

EMEA recommends Acomplia must not be used in patients on antidepressants or with major depression

Frontotemporal dementia: a new gene mutation identified

ERF, a new target for Duchenne muscular dystrophy drug therapy

Y2R inhibitor could reduce abdominal obesity

Mirtazapine and blood dyscrasias

Clozapine and myocarditis

Saxagliptin added to Metformin improves glycemic control in patients with type 2 diabetes compared to Metformin alone

FDA has approved Lyrica for treatment of fibromyalgia

Nexavar significantly extends overall survival in hepatocellular carcinoma patients

Denosumab reduces the progression of bone erosion

Alcohol intake associated with decreased risk of developing rheumatoid arthritis

IKBKE gene linked to breast cancer

Chronic iron overload: Exjade may cause acute renal failure and cytopenias

B-cell depletion therapy for patients with refractory systemic lupus erythematosus

Belimumab improves symptoms in 46 percent of systemic lupus erythematosus patients

Letrozole is active in ER-positive ovarian cancer

FDA has approved Letairis for treatment of pulmonary arterial hypertension

Lapatinib in brain metastases associated with breast cancer

Lapatinib in combination with Paclitaxel as first-line treatment for patients with metastatic or relapsed advanced breast cancer

MAGE-A3 ASCI: clinical activity of a novel cancer immunotherapeutic in patients with non-small cell lung cancer

Advanced renal cell carcinoma: Temsirolimus improves overall survival

Losartan treats muscular dystrophy in mice

Acetylsalicylic acid saves lives of cancer patients suffering myocardial infarction

SORL1, a new gene for late-onset Alzheimer's disease

Telomere length may predict risk of coronary heart disease in middle-aged men

FDA: safety information on diabetes drug Rosiglitazone

FDA has approved Lybrel, a contraceptive for continuous use

Avandia linked to risk of myocardial infarction and heart-related deaths

Pharmacogenetics of antileukemic drug toxicity

Primary gastrointestinal stromal tumor: Imatinib decreases cancer recurrence

FDA has approved Neupro patch for treatment of early Parkinson's disease

New warnings about suicidal thinking, behavior in young adults who take antidepressant medications

Avastin linked to tracheoesophageal fistula

EPCA-2 prostate cancer test more accurate than PSA testing

Huntington’s disease onset linked to faulty DNA repair

CYP1A2 inhibitors may lead to substantial increases in Tizanidine blood concentrations

Cancer: novel regulation of the common tumor suppressor PTEN

FDA has approved Altabax for topical treatment of impetigo

Novartis has agreed to stop selling Zelnorm in US

FDA has approved HepaGam B to prevent hepatitis B reinfection in liver transplant patients

Multiple myeloma: low-dose Dexamethasone combined with Lenalidomide prolongs survival compared with high-dose Dexamethasone

Humira is effective in psoriasis

Baraclude: occurrence of a resistant HIV variant in a patient co-infected with HIV and HBV

EMEA: Enzastaurin granted orphan drug status for treatment of diffuse large B-cell lymphoma

Parkinson's disease: Pergolide withdrawn for serious damage to heart valves

A new PPAR-alpha agonist shows no advantages compared with Fenofibrate

Torcetrapib fails to slow progression of coronary disease

METEOR Trial: Rosuvastatin effective at halting early atherosclerosis

COURAGE Trial: percutaneous coronary intervention adds no benefit over optimal medical therapy alone

ERASE Trial: CSL-11, a drug that mimics HDL, has mixed effect on coronary atherosclerosis

Pioglitazone, a diabetes drug, shows promise for preventing brain injury from radiation therapy

No benefit for liver cancer patients from long-acting Octreotide

FDA has approved Soliris for paroxysmal nocturnal hemoglobinuria

FDA requests label change for all sleep disorder drug products

ECG abnormalities linked with increased risk of cardiovascular events in women

FDA has approved Tykerb for advanced breast cancer patients

Increased incidence of fractures in women who received long-term treatment with Pioglitazone

Tumor-free breast tissue can have precancerous changes

Carnosinase 1 gene associated with severe kidney failure in diabetes

Pancreatic cancer surgery five-year survivors 65 and up live nearly as long as anyone

Computed tomography screening may increase rate of lung cancer diagnosis, but not decrease risk of death

FDA has approved Humira for Crohn's disease

ADHD Drugs linked to cardiovascular and psychiatric adverse events

Multple sclerosis: parasite infection may be of benefit

Osteosarcoma: no benefit to increasing dose intensity of chemotherapy

Recentin, a new angiogenesis inhibitor, can reduce size of glioblastoma

Gemcitabine appears to delay cancer recurrence following surgery for pancreatic cancer

Levofloxacin may cause dysglycemia and liver disorders

Alphanate in the treatment of von Willebrand disease

FDA has restricted use of antibiotic Ketek

Prevalence of congenital heart disease has increased strikingly in adults

Genetics and lifestyle interact to increase risk for age-related macular degeneration

Higher folate levels linked to reduced risk for Alzheimer's disease

Long-term behavioral and neurological problems associated with prenatal exposure to cocaine

Milk eliminates cardiovascular health benefits of tea

Valganciclovir for chronic fatigue syndrome to be tested

Hypertension, prehypertension in young linked with heart enlargement

Genomic alterations in the stroma of head and neck squamous cell carcinoma

NT-proBNP level was associated with a greater risk of cardiovascular events or death

Improved adherence to statins and beta-blockers associated with longer survival following myocardial infarction

Excess weight and adult weight gain increase the risk of dying from prostate cancer

Antibody therapy prevents type 1 diabetes in mouse model

Isolation of broad potential stem cells from the amniotic fluid

A novel pathway by which the anti-cancer gene p53 protects a damaged cell from becoming cancer uncovered

Risk factors for diabetes following liver transplant

A novel gene mutation associated with Wilms tumor

MTWA test can predict which patients will get life-saving benefit from ICDs, and which won't

Interferon-treated hepatitis C patients likely to experience retinopathy

Acute ST-elevation myocardial infarction: Pexelizumab does not appear to offer benefit in patients undergoing PCI

Cough and phlegm cause fourfold increase in COPD incidence

Heart failure: genetic mutation alters response to beta-blockers

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