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Ribociclib, durable reduction in distant recurrence in broad population of patients with early breast cancer

Results from an updated analysis of the pivotal phase III NATALEE trial of Ribociclib ( Kisqali ) that underscore the ...
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Nintedanib plus Docetaxel following first-line chemotherapy more or less immunotherapy in advanced NSCLC of adenocarcinoma histology

The first interim results of VARGADO, an ongoing non-interventional study in routine clinical practice in Germany evaluating the efficacy and ...
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COSMIC-HF Trial: Omecamtiv mecarbil, a novel cardiac myosin activator

COSMIC-HF ( Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure ) is a double-blind, randomized, placebo-controlled, ...
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Following a heart failure hospitalization, 44% fewer patients treated with Entresto were readmitted for heart failure within 30 days compared to those on Enalapril

Data from a new analysis demonstrating that fewer heart failure patients with reduced ejection fraction ( HFrEF ) treated with ...
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Bedaquiline and Delamanid in tuberculosis

In recent years, a pressing need to develop new, effective and safe drugs against tuberculosis ( TB ) has continued. ...
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Adjuvant chemotherapy with Gemcitabine plus Cisplatin versus Docetaxel plus Cisplatin in patients with completely resected non-small-cell lung cancer

Adjuvant chemotherapy with Vinorelbine plus Cisplatin ( VC ) improves survival in resected non-small-cell lung cancer ( NSCLC ), but ...
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PROFICIO, a clinical trial program on Evolocumab, a PCSK9 inhibitor

Evolocumab ( Repatha ) is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 ( PCSK9 ). ...
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Treatment of acute promyelocytic leukemia

Early diagnosis and treatment of acute promyelocytic leukemia ( APL ), the M3 subtype of acute myeloid leukemia ( AML ...
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Immuno-oncology: immune checkpoint inhibitors provide antitumour activity in metastatic cancers of different histologies

One of the most exciting features of immune checkpoint inhibitors ( ICIs ) is that they provide impressive tumour responses ...
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Monoclonal antibodies to PCSK9: Alirocumab in statin-intolerant patients, design and rationale of ODYSSEY ALTERNATIVE

Statin intolerance has been a major limitation in the use of statins, especially at higher doses. New effective treatments are ...
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Dalbavancin, an antibacterial treatment for patients with complicated skin and soft tissue infections

Dalbavancin ( Xydalba ) is a antibacterial treatment for patients with complicated skin and soft tissue infections ( cSSTI ) ...
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Chronic kidney disease: Sevelamer carbonate in hyperphosphataemia in adults patients

Sevelamer carbonate ( Renvela ), a buffered form of Sevelamer hydrochloride ( Renagel ), is an orally administered non-absorbed phosphate-binding ...
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Peginterferon beta-1a for the treatment of relapsing multiple sclerosis

Peginterferon beta-1a ( Plegridy ) is a new therapy that belongs to the same Interferon class as several medications that ...
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AMAGINE-1 trial: Brodalumab versus Ustekinumab in patients with moderate-to-severe plaque psoriasis

Additional results from AMAGINE-1, a pivotal, multi-arm phase 3 trial evaluating two doses of Brodalumab in patients with moderate-to-severe plaque ...
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Relvar Ellipta for the treatment of asthma and COPD, approved in Europe

European Commission has granted marketing authorisation for Relvar Ellipta, which is now licensed across 31 European countries for the following ...
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Nearly 5 million asthmatics worldwide could benefit from antifungal therapy

According to researchers from the University of Toronto and Manchester University an estimated 4,837,000 asthmatics with allergic bronchopulmonary aspergillosis ( ...
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Pembrolizumab, an investigational therapy for the treatment of advanced melanoma

Merck has announced the presentation of early interim results from a single-arm, open-label phase IB study that has so far ...
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Solid tumors: researchers have discovered new mechanism behind resistance to cancer treatment

Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors, such as those ...
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Nucleotide polymerase inhibitors for the treatment of hepatitis C virus: IDX184 clinical development Program

Idenix Pharmaceuticals has announced that it has received verbal notice from the FDA ( Food and Drug Administration ) that ...
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SVR4 of 85-100% of genotype 1 treatment naive patients treated with Sovaprevir for 12 weeks followed by an additional 12 weeks of PegInterferon plus Ribavirin

Achillion Pharmaceuticals has announced sustained viral response ( SVR4 ) results of 85 to 100% from an ongoing multi-dose Phase ...
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MedVideo
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  • Terapie innovative nelle malattie linfoproliferative: update post ASH 2021
  • Terapie immunologiche nelle neoplasie mieloidi
  • Aggiornamenti da International Myeloma Workshop 2021
  • Ruolo dell'immunoterapia nella prima linea di terapia del NSCLC
  • Resistenza batterica agli antibiotici
  • Basi per il corretto impiego degli antibiotici in Medicina Generale
  • Prospettive nella terapia di prima linea del carcinoma polmonare non a piccole cellule non-oncogene-addicted
  • Covid-19 e neoplasie ematologiche

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